The Third edition of The RNA World is freely accessible on-line, courtesy of Cold Spring Harbor Laboratory Press. Here's how to find it. Log into http://rna.cshl.edu. If it's your first visit to CSHL Press, you'll need to register, which is quick and free. If you're already registered, just enter your e-mail address. You will then see the sentence "Click here to view the Table of Contents", after which you can click on individual chapters. You can also access the chapters from the second edition (1999) that are not rewritten in the third edition; most of them have stood up very well to the test of time.
One hint: printing the chapters of The RNA World III straight from the Web page is inefficient. You get only a narrow strip of text on each page. But if you select the text and paste it into a Word document, it's extremely efficient: you can print the equivalent of two pages of the book on a single page.
Ozimek, Lukasz Krzysztof (2005) Structure-function relationships in fructosyltransferase enzymes from Lactobacillus reuteri 121 http://irs.ub.rug.nl/ppn/289755824
Contents:
Chapter 1 General introduction 11
Chapter 2 Site-directed mutagenesis study of the three catalytic residues of the fructosyltransferases of Lactobacillus reuteri 33
Chapter 3 Mutational analysis of the role of calcium ions in the Lactobacillus reuteri strain 121 fructosyltransferases (levansucrase and inulosucrase) enzymes 43
Chapter 4 The levansucrase and inulosucrase (fructosyltransferase) enzymes of Lactobacillus reuteri 121 catalyze (non-) processive transglycosylation reactions 55
Chapter 5 Engineering of the active site of inulosucrase of Lactobacillus reuteri 75
Atlas of Diseases of the Kidney; vol.15 Ed. Berl T., Bonventre J.V., Schrier R.V. Blackwell Science; 1999; pp.320; ISBN: 0632043857
Book Info (Current Medicine) Univ. of Colorado, Denver. First volume in a five-volume set. Atlas offers unique educational images including color photographs, schematics, tables, and algorithms. Volumes sold separately. Volume 2 and 5 are not published. For students, residents, and clinicians DNLM: Kidney Diseases atlases.
These sets of lectures notes on the Physics of Proteins by Hans Frauenfelder, written while Hans was a Professor at the University of Illinois at Urbana/Champaign, will soon be published by Springer Verlag, under the Editorship of Dr. Shirley Chan and Professor Robert Austin (Princeton University), and typeset by Winnie Chan of the University of Illinois at Urbana/Champaign. We invite the reader to send us their comments/corrections/additions!
Fitting Models to Biological Data Using Linear and Nonlinear Regression: A Practical Guide to Curve Fitting; ed.2 Motulsky H., Christopoulos A. Oxford University Press; 2004; pp.352; ISBN: 0195171802
Book Description Nonlinear regression is an essential tool for analyzing biological data, and is the most frequently used tool for data analysis in many labs. This book is written for biologists, not mathematical statisticians, and presents a practical approach to fitting curves with nonlinear regression. It explains how to choose a model, how to make sensible choices when using a nonlinear regression program, and how to interpret the results. It also helps you troubleshoot "bad" fits and explains how to compare models and data sets. In addition to general information about curve fitting, it also contains specific details about fitting radioligand binding, dose-response, and enzyme kinetic data, emphasizing the use of global regression. The last portion of the book explains how to fit curves with the program GraphPad Prism, but the book will be useful no matter what program you use.
From the Inside Flap "This well-written book fills a major need for biomedical researchers -- an explanation of nonlinear regression that is simple, deep, insightful and practical." Lee E. Limbird, Ph.D. Dept. Pharmacology Vanderbilt University "Because the data from many of the experiments in my laboratory are analyzed by curve fitting, it is important that my postdoctoral fellows, students and senior technicians understand the basic principles of nonlinear regression. But it has been hard for them to do so. Basic statistics books don't discuss curve fitting, advanced books on nonlinear regression tend to be too mathematical, and the manuals that come with computer programs tend to be too narrow. Motulsky and Christopolous do a excellent job of explaining the principles of curve fitting (with enough but not too much math) along with practical discussions of how to pick a model, how to make sense of results, what to do when the results appear to be nonsense and how to compare curves. I enthusiastically recommend this book to anyone doing research in pharmacology, biophysics or biochemistry -- especially for those generating dose-response, ligand binding or enzyme kinetic data (as these are discussed in detail). " David B. Bylund, Ph.D. Professor of Pharmacology University of Nebraska Medical Center
Hard on the heels of our online redesign, we have introduced several additional changes to Nature, from a complete redesign of the print version to additional content in the news section and the launch of a business section. See the changes for yourself with a free trial subscription to Nature's digital edition.